• Our Mission
    The Pediatric Brain Tumor Consortium Foundation (PBTCF) raises funds
    and provides assistance to the Pediatric Brain Tumor Consortium (PBTC)
    and its member institutions. The PBTC conducts laboratory and clinical
    research to improve treatments and find cures for pediatric brain tumors.

About the PBTCF

In the beginning, a Parent/Family committee was formed to lend its support to the PBTC – reviewing concepts and consent forms for the PBTC to ensure information was written in understandable language. In 2007, the PBTC Foundation (formerly Brain Waves) was formed by the Parent/Family Committee as a 501 (3c) nonprofit.

What We Fund

Granted funds to purchase a computer network so that PBTC information and crucial research data is available to all consortium institutions. Hardware form this 2010 grant, Protecting the Research of the Pediatric Brain Tumor Consortium, is housed at St. Jude and is crucial to the success of PBTC fast-track studies.

In 2011, the PBTCF sponsored a first-of-its-kind meeting of national experts in pediatric neuro-imaging. Insights from this meeting drive the design of future studies focused on greater accuracy for detailed diagnoses to pre-empt surgical exploration and to tailor best possible therapies.

The PBTCF underwrites a portion of the costs incurred by every child enrolled in a PBTC clinical research trial. Our ability to sponsor patients is directly related to our fluctuating annual budget.

Annual awards are presented to Clinical Research Associates (CRAs) who exceed the already rigorous standards of excellence at PBTC institutions.

Supported a scientific symposium for basic and translational scientists from PBTC member institutions held prior to the International Symposium of Pediatric Neuro-Oncology (ISPNO).

Interested Doctor

Support the PBTCF

The best way to support the Pediatric Brain Tumor Consortium Foundation is to either make a donation or associate PBTCF with your Amazon Smile account as your charity of choice. Amazon will donate 0.5% of eligible purchases to PBTCF when shopping through smile.amazon.com. Add PBTCF today by visiting https://smile.amazon.com/ch/20-8573849

Current PBTC Clinical Trials

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration
recruiting

Feasibility Trial of Optune for Children With Recurrent or Progressive Supratentorial High-Grade Glioma and Ependymoma
recruiting

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
recruiting

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
recruiting

Phase I Study of APX005M in Pediatric CNS Tumors
recruiting

Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE
recruiting

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
recruiting

Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
recruiting

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors
recruiting

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma
not yet recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma
not yet recruiting

HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma
not yet recruiting

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
active, not recruiting

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
active, not recruiting

Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System
active, not recruiting

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Partners

Funding for the PBTCF is made possible by the continued support
of our partner charities.

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Contact Us

Pediatric Brain Tumor Consortium Foundation
10280 Chester Road
Cincinnati, Ohio 45215

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